http://news.sciencemag.org/biology/2014/10/giving-shapes-signaling-proteins?utm_campaign=email-news-latest&utm_source=eloqua
"Some 40% of all approved drugs target the proteins called G protein-coupled receptors (GPCRs), which relay signals across the cell membrane. But we know the 3D shapes of just 22 of the estimated 826 human GPCRs. This week, a trio of U.S. and Chinese academic institutions announced that they’ll join forces over the next 5 years with three pharmaceutical companies to determine the structures of 200 more."
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